Protein Alignment CG5255 and ACR

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 74/260 - (28%)
• Similarity: 124/260 - (47%)
• Gaps: 27/260 - (10%)

  Fly     1 MLLILLPLVLFTSSAASQILYPPQYTKN-----RIVGGEEAAAGLAPYQISLQGIGSGA---HSC 57
            :||:|...|:...:|........::.:|     |||||:.|..|..|:.:|||.....:   |:|
Human     9 ILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTC 73

  Fly    58 GGAIIDERWIITAAHCTRGR-QATAFRVLTGTQDLHQNGSK-------YYYPDRIVEHSNYAPRK 114
            ||::::.||::|||||..|: ....:|::.|.:::....:|       ..|.::|:.|..|....
Human    74 GGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSAT 138

  Fly   115 YRNDIALLHLNESIVFDNATQPVELDH-EALVP-GSR-LLLTGWGTLSLGGDVPAR-LQSLEVNY 175
            ..|||||:.:...|.......|..|.| :|.:| ||: ..:.|||.:......|:. |....|:.
Human   139 EGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDL 203

  Fly   176 VPFEQCRAAHDNSTRVDIGHVCTFNDKGR-GACHGDSGGPLVHNGK------LVALVNWGLPCAK 233
            :..:.|.:....:.||...:||.....|: ..|.|||||||:....      :|.:.:||:.||:
Human   204 IDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCAR 268

  Fly   234  233
            Human   269  268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	68/227 (30%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	68/227 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421