Protein Alignment CG5255 and PRSS57

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 72/253 - (28%)
• Similarity: 111/253 - (43%)
• Gaps: 23/253 - (9%)

  Fly     7 PLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERWIITAA 71
            ||:...::....:..|......:|:||.|......||..|::  ..|.|.|||.::..||:::||
Human    11 PLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVR--FGGQHHCGGFLLRARWVVSAA 73

  Fly    72 HCTRGRQATAFRVLTGTQDLH--QNGSKYYYPDRIVEHSNYAPRKYRNDIALLHLNESIVFDNAT 134
            ||...|......|:.|...|.  :...:.:..|.:..|.:|.|..:.|||.||.||.|.|...|.
Human    74 HCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV 138

  Fly   135 ---QPVELDHEALVPGSRLLLTGWGTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVDIGH- 195
               :|..........|:|..:.|||.:|...::|..|...:|..:..:.|.::..       ||
Human   139 GLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWK-------GHL 196

  Fly   196 ----VCTFNDKG--RGACHGDSGGPLVHNGKLVALVNW-GLPCA-KGYPDAHASISYY 245
                :||.:...  ||.|..|||||||...:...||:: ||.|. ...||.:..:|.:
Human   197 TLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAF 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	69/231 (30%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	69/230 (30%)