Protein Alignment CG5255 and KLK1

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 74/255 - (29%)
• Similarity: 125/255 - (49%)
• Gaps: 38/255 - (14%)

  Fly     2 LLILLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERW 66
            |::.|.|.|..:.||     ||  .::|||||.|......|:|.:|....:  ..|||.::..:|
Human     4 LVLCLALSLGGTGAA-----PP--IQSRIVGGWECEQHSQPWQAALYHFST--FQCGGILVHRQW 59

  Fly    67 IITAAHCTRGRQATAFRVLTGTQDL--HQNGSKYYYPDR-----------IVEHSNYAPRKYRND 118
            ::|||||.    :..:::..|..:|  .:|.:::.:...           :..|:..|...|.:|
Human    60 VLTAAHCI----SDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120

  Fly   119 IALLHLNE-SIVFDNATQPVELDHEALVPGSRLLLTGWGTLSLGG-DVPARLQSLEVNYVPFEQC 181
            :.||.|.| :....:|.:.|||..|....||..|.:|||::.... ..|..||.:::..:|.::|
Human   121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185

  Fly   182 RAAHDNST---RVDIGHVCTFNDKGRGACHGDSGGPLVHNGKLVALVNWG-LPCAKGYPD 237
            :.||....   .:.:||:    :.|:..|.|||||||:.:|.|..:.:|| :||  |.|:
Human   186 KKAHVQKVTDFMLCVGHL----EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPC--GTPN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	66/228 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	65/227 (29%)