Protein Alignment CG5255 and HABP2

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 85/306 - (27%)
• Similarity: 133/306 - (43%)
• Gaps: 78/306 - (25%)

  Fly    12 TSSAASQILYPPQ-----YTK-----------------NRIVGGEEAAAGLAPYQISLQ------ 48
            ::.:|..:.||.:     .||                 .||.||.::.||..|:|.|||
Human   274 SACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLT 338

  Fly    49 -GIGSGAHSCGGAIIDERWIITAAHCTRGRQATAFRVLTGTQDL-----HQNGSKYYYPDRIVEH 107
             .:..| |.||||:|...|::|||||| ..:....:|:.|.|||     |:..   :..::|.::
Human   339 ISMPQG-HFCGGALIHPCWVLTAAHCT-DIKTRHLKVVLGDQDLKKEEFHEQS---FRVEKIFKY 398

  Fly   108 SNYAPRKY--RNDIALLHLNESIVFDNATQPVELDHEAL---------VP------GSRLLLTGW 155
            |:|..|..  .||||||.|          :||: .|.||         :|      ||...::||
Human   399 SHYNERDEIPHNDIALLKL----------KPVD-GHCALESKYVKTVCLPDGSFPSGSECHISGW 452

  Fly   156 GTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVDIGHVCTFN--DKGRGACHGDSGGPLV-- 216
            |....|.. ..:|...:|..:....|.:.......:|...:|..|  ..|:..|.|||||||.
Human   453 GVTETGKG-SRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCE 516

  Fly   217 HNGK--LVALVNWGLPCAKGYPDAHASISYYHDFIRTHLSLSKTDS 260
            .:|.  :..:|:|||.|.| .|..:..::.:.::|:..:   |::|
Human   517 KDGTYYVYGIVSWGLECGK-RPGVYTQVTKFLNWIKATI---KSES 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	77/254 (30%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	0/2 (0%)
		Tryp_SPc	314..553	CDD:238113	77/256 (30%)