Protein Alignment CG5255 and PRSS33

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 92/284 - (32%)
• Similarity: 136/284 - (47%)
• Gaps: 42/284 - (14%)

  Fly     2 LLILLPLVLFT-------SSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGG 59
            |.:||.|||..       |:|..|    |:.: :|||||.:...|..|:|.|:|  ..|||.|||
Human     7 LQVLLLLVLGAAGTQGRKSAACGQ----PRMS-SRIVGGRDGRDGEWPWQASIQ--HRGAHVCGG 64

  Fly    60 AIIDERWIITAAHCTRGRQATA-FRVLTGTQDLHQNGSKYYYPD--RIVEHSNYAPRKYRNDIAL 121
            ::|..:|::|||||...|...| :||..|...|.....:.....  |::...:|:....|.|:||
Human    65 SLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLAL 129

  Fly   122 LHLNESIVFDNATQPVELDHEALVPGSR------LLLTGWGTLSLGGDVP--ARLQSLEVNYVPF 178
            |.|...:......|||.|.    |||:|      ..:||||:|..|..:|  ..||.:.|..:..
Human   130 LQLRRPVPLSARVQPVCLP----VPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDS 190

  Fly   179 EQCRAAH------DNSTRVDI-GHVCTFNDKG-RGACHGDSGGPL--VHNGK--LVALVNWGLPC 231
            ..|...:      ..:.|:.: |.:|....:| :.||.|||||||  :.:|.  ||.:|:||..|
Human   191 RTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGC 255

  Fly   232 A-KGYPDAHASISYYHDFIRTHLS 254
            | ...|..:.|::.|..:|:..:|
Human   256 ALPNRPGVYTSVATYSPWIQARVS 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	80/243 (33%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	79/243 (33%)