Protein Alignment CG5255 and KLK5

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 66/231 - (28%)
• Similarity: 116/231 - (50%)
• Gaps: 13/231 - (5%)

  Fly    26 TKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERWIITAAHCTRGRQATAFRVLTGTQD 90
            :.:||:.|.:......|:|.:|. :......||..::..:|::|||||.:    ..|||..|...
Human    63 SSSRIINGSDCDMHTQPWQAALL-LRPNQLYCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYS 122

  Fly    91 L---HQNGSKYYYPDRIVEHSNYAPRKYRNDIALLHLNESIVFDNATQPVELDHEALVPGSRLLL 152
            |   :::|.:.:...:.:.|..|:...:.||:.|:.||..|......:|:.:.......|::.|:
Human   123 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLV 187

  Fly   153 TGWGTL-SLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVDIGHVCTFNDKGRGACHGDSGGPLV 216
            :||||. |.....|..||.|.::.:..::|..|:..  ::|....|..:..||.:|.||||||:|
Human   188 SGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR--QIDDTMFCAGDKAGRDSCQGDSGGPVV 250

  Fly   217 HNGKLVALVNWG-LPCAK-GYPDAHASISYYHDFIR 250
            .||.|..||:|| .|||: ..|..:.::..:..:|:
Human   251 CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	65/225 (29%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/4 (25%)
		Tryp_SPc	66..285	CDD:214473	65/225 (29%)