DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5255 and CG30091

DIOPT Version :9

Sequence 1:	NP_650604.1	Gene:	CG5255 / 42073	FlyBaseID:	FBgn0038485	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	71/274 - (25%)
Similarity:	122/274 - (44%)	Gaps:	33/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LILLPLVLFTSSAASQILYP----PQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIID 63
            ::|...:|.....::::|..    |.....:||||.:|.....|:...::  .:....|||::|.
  Fly     6 VVLFAWMLTAGRGSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIK--TNDEFICGGSVIT 68

  Fly    64 ERWIITAAHCTRGRQA-----TAFRVLTGTQDL-----HQNGSKYYYPDRIVEHSNYAPRKYRND 118
            .::::|||||....:.     |...|..|...|     |.:..:.|..:|:..|.::|.:.||||
  Fly    69 NKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRND 133

  Fly   119 IALLHLNESIVFDNATQPV-ELDHEALVPGSRLL----LTGWGTLSLGGDVPARLQSLEVNYVPF 178
            ||||.|.:|||:....:|: .|.::.|.|.:.|:    ..|||... .|.:...||.:::..:..
  Fly   134 IALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTG-NGKMSNNLQMVKIYRIDR 197

  Fly   179 EQCRAAHDNSTRVDIGHVCTFNDKGRGACHGDSGGPL--------VHNGKLVALVNWGLPCAKGY 235
            :.|.||...:  .|....|.....||..|..||||||        :.....:.:|:.|....:|:
  Fly   198 KMCEAAFWYT--FDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGF 260

  Fly   236 PDAHASISYYHDFI 249
             ..:..:..:.|||
  Fly   261 -GMYTDVMGHIDFI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	65/242 (27%)
CG5255	NP_650604.1	Tryp_SPc	30..252	CDD:238113	67/243 (28%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	65/242 (27%)
		Tryp_SPc	37..276	CDD:238113	67/243 (28%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940