Protein Alignment CG5246 and PRSS27

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 83/287 - (28%)
• Similarity: 129/287 - (44%)
• Gaps: 46/287 - (16%)

  Fly     6 LISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGG 70
            |:.:|...||.:..:....|...||          |::||.|:..|..|:||||... |.|.|||
Human     9 LLLLLCFGSQRAKAATACGRPRMLN----------RMVGGQDTQEGEWPWQVSIQRN-GSHFCGG 62

  Fly    71 SIIAPQWILTAAHCME--WPIQYLKIVTGTVDYTRPGAEYLVDGSKIHCSHDKPAYHN-----DI 128
            |:||.||:||||||..  ......:::.|.....:||...:.  :::......|.|..     |:
Human    63 SLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMY--ARVRQVESNPLYQGTASSADV 125

  Fly   129 ALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQ--------LQKIDLN 185
            ||:....|:.:.:...|:.|.....:.:.|....:|||||.      |.:        |||:.:.
Human   126 ALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSP------SEEDLLPEPRILQKLAVP 184

  Fly   186 YIDHDNCQ---SRVRNANW----LSEGHVCTFTQEG-EGSCHGDSGGP---LVDANQTLVGVVNW 239
            .||...|.   |:.....:    :....:|...:|| :.:|.||||||   ||..:....||::|
Human   185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISW 249

  Fly   240 GEACA-IGYPDVFGSVAYYHDWIEQMM 265
            ||.|| ...|.|:..|..:|:||.:::
Human   250 GEGCARQNRPGVYIRVTAHHNWIHRII 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	75/247 (30%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	75/247 (30%)