Protein Alignment CG5246 and Tmprss5

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001346389.1
• Gene: Tmprss5 / 80893
• MGIID: 1933407
• Length: 455
• Species: Mus musculus
• Alignment Length: 281
• Identity: 82/281 - (29%)
• Similarity: 123/281 - (43%)
• Gaps: 56/281 - (19%)

  Fly     1 MKCLVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGE 65
            :||          |:|.|:.:                 .:|::||....:|..|:|.|:| ....
Mouse   204 LKC----------SECGARPL-----------------ASRIVGGQAVASGRWPWQASVM-LGSR 240

  Fly    66 HVCGGSIIAPQWILTAAHCM---------EWPIQYLKIVTGTVDYTRPGAEYLVDGSKIHCSHDK 121
            |.||.|::||.|::||||||         .|     ::..|.|.:   ||.....|:.:......
Mouse   241 HTCGASVLAPHWVVTAAHCMYSFRLSRLSSW-----RVHAGLVSH---GAVRQHQGTMVEKIIPH 297

  Fly   122 PAY----HN-DIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQ-LQ 180
            |.|    |: |:||:....||.:.|....:.|.:|......|.:..::|||.|.....:|:. ||
Mouse   298 PLYSAQNHDYDVALLQLRTPINFSDTVGAVCLPAKEQHFPWGSQCWVSGWGHTDPSHTHSSDTLQ 362

  Fly   181 KIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEG-SCHGDSGGPLV-DANQT--LVGVVNWGE 241
            ...:..:....|.|....:..|:...:|....:|.. :|.|||||||| .:..|  |||||:||.
Mouse   363 DTMVPLLSTYLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGR 427

  Fly   242 ACA-IGYPDVFGSVAYYHDWI 261
            .|| ...|.|:..||.:.|||
Mouse   428 GCAEPNRPGVYAKVAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	76/240 (32%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:464747	5/18 (28%)
		Tryp_SPc	217..448	CDD:214473	75/239 (31%)