Protein Alignment CG5246 and PRSS56

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 75/271 - (27%)
• Similarity: 122/271 - (45%)
• Gaps: 50/271 - (18%)

  Fly    34 GHVKPET--------RVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHC-MEWPI 89
            |..:|.|        |::||..:|.|..|:.|. :...|:.:|||.::|..|:|||||| :..|.
Human    89 GERRPSTANVTRAHGRIVGGSAAPPGAWPWLVR-LQLGGQPLCGGVLVAASWVLTAAHCFVGAPN 152

  Fly    90 QYLKIVTGTVDYTRPGAEYLVDGSK-------------IHCSHDKPAYHNDIALIHTAKPIVYDD 141
            :.|..||            |.:||:             .|...|...:|||:||:....|:....
Human   153 ELLWTVT------------LAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGG 205

  Fly   142 LTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSR----VRNANWL 202
            ..:|:.|..:...|..|....:.|||:....|..:..:::..:..:..|.|:..    :|.:..|
Human   206 SARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTML 270

  Fly   203 SEGHVCTFTQEGEGSCHGDSGGPLVDA------NQTLVGVVNWGEACA-IGYPDVFGSVAYYHDW 260
            ..|::.    .|..||.|||||||..:      .:.|.||.:||:.|. .|.|.|:..||.:.||
Human   271 CAGYLA----GGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDW 331

  Fly   261 IEQMMTDAGTA 271
            :::.|:.|.::
Human   332 LQEQMSAASSS 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	69/245 (28%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	69/246 (28%)
		PksD	<178..600	CDD:442550	46/169 (27%)