Protein Alignment CG5246 and TPSB2

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 76/294 - (25%)
• Similarity: 122/294 - (41%)
• Gaps: 66/294 - (22%)

  Fly     4 LVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVS--IMNTFGEH 66
            |:|:::.|:.|:..|....           |.......::||.::|....|:|||  :.:.:..|
Human     4 LLLLALPVLASRAYAAPAP-----------GQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMH 57

  Fly    67 VCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTV--------DYTRPGAEYLVDGSKIHCSHDKPA 123
            .||||:|.|||:||||||:...::.|..:...:        |...|.:..:|          .|.
Human    58 FCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIV----------HPQ 112

  Fly   124 YHN-----DIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYST--QLQK 181
            ::.     ||||:...:|:........:.|.........|....:||||......|...  .|::
Human   113 FYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQ 177

  Fly   182 IDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEG---------------EGSCHGDSGGPLV-DAN 230
            :.:..:::..|.::.         |:..:|.:.               ..||.|||||||| ..|
Human   178 VKVPIMENHICDAKY---------HLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVN 233

  Fly   231 QTLV--GVVNWGEACA-IGYPDVFGSVAYYHDWI 261
            .|.:  |||:|||.|| ...|.::..|.||.|||
Human   234 GTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	70/256 (27%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	70/256 (27%)