Protein Alignment CG5246 and PRSS22

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 78/257 - (30%)
• Similarity: 120/257 - (46%)
• Gaps: 38/257 - (14%)

  Fly    37 KPE--TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQ--YL-KIVT 96
            ||:  .||:||.||.....|:.|||... |.|.|.||::..:|::|||||.:..:.  || .::.
Human   151 KPQQLNRVVGGEDSTDSEWPWIVSIQKN-GTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLL 214

  Fly    97 GTVDYTRPGAEYLVDGSKIHCS--HDKPAYH------NDIALIHTAKPIVYDDLTQPIKLASKGS 153
            |......||:.    ..|:..:  ...|.|.      .||||:...:.|.:.:...||.|.....
Human   215 GAWQLGNPGSR----SQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASI 275

  Fly   154 LPKVGDKLTLTGWGSTKTWG---RYSTQLQKIDLNYIDHDNCQSRVRNANW-------LSEGHVC 208
            .........::||||.:. |   .:...|||:.:..||.:.|.    :..|       ::|..:|
Human   276 HLPPNTHCWISGWGSIQD-GVPLPHPQTLQKLKVPIIDSEVCS----HLYWRGAGQGPITEDMLC 335

  Fly   209 TFTQEGE-GSCHGDSGGPL---VDANQTLVGVVNWGEACA-IGYPDVFGSVAYYHDWIEQMM 265
            ....||| .:|.|||||||   ||....|.|:::|||.|| ...|.|:.|::.:..|:|:::
Human   336 AGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	74/246 (30%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	75/247 (30%)