Protein Alignment CG5246 and Klk4

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_064312.1
• Gene: Klk4 / 56640
• MGIID: 1861379
• Length: 255
• Species: Mus musculus
• Alignment Length: 274
• Identity: 74/274 - (27%)
• Similarity: 134/274 - (48%)
• Gaps: 47/274 - (17%)

  Fly     3 CLVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHV 67
            ||:|     .::..||.||                 .:|:|.|.|......|:|.::.:..| ..
Mouse    15 CLIL-----EVTGASASSV-----------------SSRIIQGQDCSPHSQPWQAALFSEDG-FF 56

  Fly    68 CGGSIIAPQWILTAAHCMEWPIQY-----LKIVTGTVDYTRPGAEYLVDGSKI-HCSHDKPAYHN 126
            |.|.::.|||:|:||||::  ..|     |..:.|:.:   ||:..|.....| |.:.:.|::.|
Mouse    57 CSGVLVHPQWVLSAAHCLQ--ESYIVGLGLHNLKGSQE---PGSRMLEAHLSIQHPNFNDPSFAN 116

  Fly   127 DIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDN 191
            |:.||...:.::..:..:.|.:|::  .|..||...::|||..|. |:..:.||.::|:....:.
Mouse   117 DLMLIKLNESVIESNTIRSIPVATQ--CPTPGDTCLVSGWGQLKN-GKLPSLLQCVNLSVASEET 178

  Fly   192 CQ---SRVRNANWLSEGHVCTFTQEGEGSCHGDSGGPLVDANQTLVGVVNWGEA-CA-IGYPDVF 251
            |:   ..|.:.:....|.    .|:.:.||:||||||:| .|::|.|:|:.|:. |. .|.|.|:
Mouse   179 CRLLYDPVYHLSMFCAGG----GQDQKDSCNGDSGGPIV-CNRSLQGLVSMGQGKCGQPGIPSVY 238

  Fly   252 GSVAYYHDWIEQMM 265
            .::..:.:||:.::
Mouse   239 TNLCKFTNWIQTII 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	66/231 (29%)
Klk4	NP_064312.1	Tryp_SPc	32..251	CDD:238113	66/232 (28%)