Protein Alignment CG5246 and AZU1

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001691.1
• Gene: AZU1 / 566
• HGNCID: 913
• Length: 251
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 63/239 - (26%)
• Similarity: 104/239 - (43%)
• Gaps: 21/239 - (8%)

  Fly    38 PETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLK-IVTGTVDY 101
            |...::||..:.....|:..||.|. |.|.|||::|..::::|||.|.:.....:. :|.|..|.
Human    23 PLLDIVGGRKARPRQFPFLASIQNQ-GRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 86

  Fly   102 ---TRPGAEYLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTL 163
               .|...:.....|.....:|.....||:.|:...:..........:.|..:.:..:.|.:..:
Human    87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQV 151

  Fly   164 TGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT--FTQEGEGSCHGDSGGPL 226
            .||||.::.||.|...:.:::.....|.|:          ..:|||  .|:.| |.|:||.|.||
Human   152 AGWGSQRSGGRLSRFPRFVNVTVTPEDQCR----------PNNVCTGVLTRRG-GICNGDGGTPL 205

  Fly   227 VDANQTLVGVVNWG-EACAIGYPDVFGSVAYYHDWIEQMMTDAG 269
            | ......||.::. ..|..| ||.|..||.:.|||:.::.:.|
Human   206 V-CEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWIDGVLNNPG 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	61/227 (27%)
AZU1	NP_001691.1	Tryp_SPc	27..240	CDD:238113	60/226 (27%)
		Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327	46..70		11/24 (46%)