Protein Alignment CG5246 and KLK10

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 63/241 - (26%)
• Similarity: 108/241 - (44%)
• Gaps: 48/241 - (19%)

  Fly    51 GFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTRPGAEYLV----- 110
            |..|:|||:.|....| |.|.::...|:||||||...|:           :.|.|.::|:
Human    55 GSQPWQVSLFNGLSFH-CAGVLVDQSWVLTAAHCGNKPL-----------WARVGDDHLLLLQGE 107

  Fly   111 -----DGSKIHCSHDKPAYH-------------NDIALIHTAKPIVYDDLTQPIKLASKGSLPKV 157
                 ..|.:|     |.||             :|:.|:..|:|:|.....:.::|..:.:.|
Human   108 QLRRTTRSVVH-----PKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP-- 165

  Fly   158 GDKLTLTGWGSTKTWG-RYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGD 221
            ||:..:.|||:|.... :|:..|....:..:....|:  |.....::...:|.....|:..|..|
Human   166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE--VFYPGVVTNNMICAGLDRGQDPCQSD 228

  Fly   222 SGGPLVDANQTLVGVVNWG-EAC-AIGYPDVFGSVAYYHDWIEQMM 265
            |||||| .::||.|:::|| ..| :..:|.|:..:..|..||.:::
Human   229 SGGPLV-CDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	63/237 (27%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	63/238 (26%)