DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5246 and KLK10

DIOPT Version :9

Sequence 1:NP_650603.1 Gene:CG5246 / 42072 FlyBaseID:FBgn0038484 Length:272 Species:Drosophila melanogaster
Sequence 2:NP_001070968.1 Gene:KLK10 / 5655 HGNCID:6358 Length:276 Species:Homo sapiens


Alignment Length:241 Identity:63/241 - (26%)
Similarity:108/241 - (44%) Gaps:48/241 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 GFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTRPGAEYLV----- 110
            |..|:|||:.|....| |.|.::...|:||||||...|:           :.|.|.::|:     
Human    55 GSQPWQVSLFNGLSFH-CAGVLVDQSWVLTAAHCGNKPL-----------WARVGDDHLLLLQGE 107

  Fly   111 -----DGSKIHCSHDKPAYH-------------NDIALIHTAKPIVYDDLTQPIKLASKGSLPKV 157
                 ..|.:|     |.||             :|:.|:..|:|:|.....:.::|..:.:.|  
Human   108 QLRRTTRSVVH-----PKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP-- 165

  Fly   158 GDKLTLTGWGSTKTWG-RYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGD 221
            ||:..:.|||:|.... :|:..|....:..:....|:  |.....::...:|.....|:..|..|
Human   166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE--VFYPGVVTNNMICAGLDRGQDPCQSD 228

  Fly   222 SGGPLVDANQTLVGVVNWG-EAC-AIGYPDVFGSVAYYHDWIEQMM 265
            |||||| .::||.|:::|| ..| :..:|.|:..:..|..||.:::
Human   229 SGGPLV-CDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVI 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5246NP_650603.1 Tryp_SPc 41..261 CDD:214473 61/235 (26%)
Tryp_SPc 42..263 CDD:238113 63/237 (27%)
KLK10NP_001070968.1 Tryp_SPc 49..272 CDD:238113 63/238 (26%)
Tryp_SPc 49..269 CDD:214473 61/235 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.