Protein Alignment CG5246 and PRSS8

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 85/265 - (32%)
• Similarity: 134/265 - (50%)
• Gaps: 49/265 - (18%)

  Fly    36 VKPETRVIGGVDSPTGFAPYQVSIMNTF-GEHVCGGSIIAPQWILTAAHCMEWPIQY------LK 93
            |.|:.|:.||..:..|..|:||||  |: |.||||||:::.||:|:||||  :|.::      :|
Human    39 VAPQARITGGSSAVAGQWPWQVSI--TYEGVHVCGGSLVSEQWVLSAAHC--FPSEHHKEAYEVK 99

  Fly    94 IVTGTVD-YTR-----------PGAEYLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPI 146
            :....:| |:.           |...||.:||:           .||||:..::||.:....:||
Human   100 LGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ-----------GDIALLQLSRPITFSRYIRPI 153

  Fly   147 KL-ASKGSLPKVGDKLTLTGWGSTKTWGRYST--QLQKIDLNYIDHDNC------QSRVRNANWL 202
            .| |:..|.|. |...|:||||.........|  .||::::..|..:.|      .::....:::
Human   154 CLPAANASFPN-GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFV 217

  Fly   203 SEGHVCT-FTQEGEGSCHGDSGGPL---VDANQTLVGVVNWGEAC-AIGYPDVFGSVAYYHDWIE 262
            .|..||. :.:.|:.:|.|||||||   |:....|.|:|:||:|| |...|.|:...:.|..||:
Human   218 QEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282

  Fly   263 QMMTD 267
            ..:|:
Human   283 SKVTE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	81/253 (32%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	81/254 (32%)