Protein Alignment CG5246 and KLK7

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 67/240 - (27%)
• Similarity: 110/240 - (45%)
• Gaps: 34/240 - (14%)

  Fly    41 RVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTRPG 105
            ::|.|.....|..|:||::::....| |||.::..:|:||||||        |:...||..   |
Human    29 KIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHC--------KMNEYTVHL---G 81

  Fly   106 AEYLVD-------GSKI--HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKL 161
            ::.|.|       .||.  |..:....:.||:.|:..........:.:.::|.|:...|  |...
Human    82 SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP--GTTC 144

  Fly   162 TLTGWGSTKTWG-RYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGG 224
            |::|||:|.:.. .:.:.|..:|:..|...:|....::.  |....:|. .....:.:|:|||||
Human   145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL--LENSMLCAGIPDSKKNACNGDSGG 207

  Fly   225 PLVDANQTLVGVVNWGE-ACAIGYPD---VFGSVAYYHDWIEQMM 265
            ||| ...||.|:|:||. .|  |.|:   |:..|..:..||...|
Human   208 PLV-CRGTLQGLVSWGTFPC--GQPNDPGVYTQVCKFTKWINDTM 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	66/235 (28%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	64/234 (27%)