DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5246 and PRSS2

DIOPT Version :9

Sequence 1:NP_650603.1 Gene:CG5246 / 42072 FlyBaseID:FBgn0038484 Length:272 Species:Drosophila melanogaster
Sequence 2:NP_001290343.1 Gene:PRSS2 / 5645 HGNCID:9483 Length:261 Species:Homo sapiens


Alignment Length:245 Identity:78/245 - (31%)
Similarity:121/245 - (49%) Gaps:32/245 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 ETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTR 103
            :.:::||........|||||:.:  |.|.||||:|:.||:::|.||.:..|. .|:.....:|.|
Human    21 DDKIVGGYICEENSVPYQVSLNS--GYHFCGGSLISEQWVVSAGHCYKSAIN-SKLSGRGCEYHR 82

  Fly   104 -------------PGAEYLVDGSKI--HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGS 153
                         .|.|..::.:||  |..::.....|||.||..:.|.|.:.....|.|.:  :
Human    83 IQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPT--A 145

  Fly   154 LPKVGDKLTLTGWGSTKTWGR-YSTQLQKIDLNYIDHDNCQS----RVRNANWLSEGHVCTFTQE 213
            .|..|.:..::|||:|.:.|. |..:||.:|...:....|::    ::.| |....|    |.:.
Human   146 PPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN-NMFCVG----FLEG 205

  Fly   214 GEGSCHGDSGGPLVDANQTLVGVVNWGEACA-IGYPDVFGSVAYYHDWIE 262
            |:.||.||||||:| :|..|.|:|:||..|| ...|.|:..|..|.|||:
Human   206 GKDSCQGDSGGPVV-SNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5246NP_650603.1 Tryp_SPc 41..261 CDD:214473 76/240 (32%)
Tryp_SPc 42..263 CDD:238113 78/242 (32%)
PRSS2NP_001290343.1 Tryp_SPc 23..253 CDD:214473 76/240 (32%)
Tryp_SPc 24..256 CDD:238113 78/242 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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