Protein Alignment CG5246 and PRSS1

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 75/229 - (32%)
• Similarity: 120/229 - (52%)
• Gaps: 14/229 - (6%)

  Fly    39 ETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTR 103
            :.:::||.:......|||||:.:  |.|.||||:|..||:::|.||.:..|| :::....::...
Human    21 DDKIVGGYNCEENSVPYQVSLNS--GYHFCGGSLINEQWVVSAGHCYKSRIQ-VRLGEHNIEVLE 82

  Fly   104 PGAEYLVDGSKI--HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGW 166
             |.|..::.:||  |..:|:...:|||.||..:...|.:.....|.|.:  :.|..|.|..::||
Human    83 -GNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPT--APPATGTKCLISGW 144

  Fly   167 GSTKTWGR-YSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGGPLVDA 229
            |:|.:.|. |..:||.:|...:....|::.....  ::....|. |.:.|:.||.||||||:| .
Human   145 GNTASSGADYPDELQCLDAPVLSQAKCEASYPGK--ITSNMFCVGFLEGGKDSCQGDSGGPVV-C 206

  Fly   230 NQTLVGVVNWGEACA-IGYPDVFGSVAYYHDWIE 262
            |..|.|||:||:.|| ...|.|:..|..|..||:
Human   207 NGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	75/226 (33%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	73/224 (33%)