Protein Alignment CG5246 and Cfd

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 237
• Identity: 66/237 - (27%)
• Similarity: 111/237 - (46%)
• Gaps: 10/237 - (4%)

  Fly    37 KPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPI--QYLKIVTGTV 99
            :|..|::||.::.....||..|: ...|.|||||:::..||:|:|||||:...  :.::::.|..
  Rat    21 QPRGRILGGQEAMAHARPYMASV-QVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAH 84

  Fly   100 DYTRPGAE---YLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKL 161
            ..:.|...   |.|....:|......:..:|:.|...:.........:|:.|..:....|.|...
  Rat    85 SLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGTLC 149

  Fly   162 TLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGDSGGPL 226
            .:.|||.....||....||::.::.:|.:.|..|..:...:::..:|..:...: :|.|||||||
  Rat   150 DVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRD-TCRGDSGGPL 213

  Fly   227 VDANQTLVGVVNWG-EACA-IGYPDVFGSVAYYHDWIEQMMT 266
            | ....:..||.|| ..|. ...|.||..||.|..|||.:::
  Rat   214 V-CGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	63/227 (28%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	64/228 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)