Protein Alignment CG5246 and KLK12

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 63/234 - (26%)
• Similarity: 97/234 - (41%)
• Gaps: 39/234 - (16%)

  Fly    41 RVIGGVDSPTGFAPYQVSIMNTFGEHV-CGGSIIAPQWILTAAHC----------------MEWP 88
            ::..|.:......|:||.:..  |..: |||.:|..:|:||||||                ::|.
Human    21 KIFNGTECGRNSQPWQVGLFE--GTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWT 83

  Fly    89 IQYLKIVTGTVDYTRPGAEYLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGS 153
            .|   |.......|.||  ||  |:.  .||:     :|:.|:....|:......||:.|.:  .
Human    84 EQ---IRHSGFSVTHPG--YL--GAS--TSHE-----HDLRLLRLRLPVRVTSSVQPLPLPN--D 132

  Fly   154 LPKVGDKLTLTGWGSTK-TWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGS 217
            ....|.:..::|||.|. ....:...||.::|:.:.|..|.......  ::...||.....|:.:
Human   133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGR--ITSNMVCAGGVPGQDA 195

  Fly   218 CHGDSGGPLVDANQTLVGVVNWGEACAIGYPDVFGSVAY 256
            |.|||||||| ....|.|:|:||.....|...:.|...|
Human   196 CQGDSGGPLV-CGGVLQGLVSWGSVGPCGQDGIPGVYTY 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	63/233 (27%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	63/233 (27%)