DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5246 and KLK14

DIOPT Version :9

Sequence 1:NP_650603.1 Gene:CG5246 / 42072 FlyBaseID:FBgn0038484 Length:272 Species:Drosophila melanogaster
Sequence 2:NP_001298111.2 Gene:KLK14 / 43847 HGNCID:6362 Length:251 Species:Homo sapiens


Alignment Length:237 Identity:76/237 - (32%)
Similarity:121/237 - (51%) Gaps:16/237 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 ETRVIGGVDSPTGFAPYQVSIM-NTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYT 102
            |.::|||........|:|.::: ......:|||::::.||::|||||.. ||  |::..|..:..
Human    22 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGR-PI--LQVALGKHNLR 83

  Fly   103 RPGAE---YLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLT 164
            |..|.   ..|.....|.:::...:.||:.|:...:|.......:||::....:.|  |....::
Human    84 RWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP--GTSCRVS 146

  Fly   165 GWGS-TKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGGPLV 227
            |||: :....||...||.:::|....:.||......  ::.|.||. ..|.|:.||.||||||||
Human   147 GWGTISSPIARYPASLQCVNINISPDEVCQKAYPRT--ITPGMVCAGVPQGGKDSCQGDSGGPLV 209

  Fly   228 DANQTLVGVVNWG-EACAI-GYPDVFGSVAYYHDWIEQMMTD 267
            ...| |.|:|:|| |.||: |||.|:.::..|..|||:.|.|
Human   210 CRGQ-LQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRD 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5246NP_650603.1 Tryp_SPc 41..261 CDD:214473 70/227 (31%)
Tryp_SPc 42..263 CDD:238113 72/228 (32%)
KLK14NP_001298111.2 Tryp_SPc 25..247 CDD:238113 73/229 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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