DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and CG9737

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	73/300 - (24%)
Similarity:	132/300 - (44%)	Gaps:	67/300 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RRHQLNHHLGHVKPET--------------RVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAP 75
            :|.:|...:..|:|.:              |:.||..:.....|:...::....::.|.|::|..
  Fly   119 KRKKLKRRIQTVEPSSGFNLLNECGKQVTNRIYGGEIAELDEFPWLALLVYNSNDYGCSGALIDD 183

  Fly    76 QWILTAAHCMEWP-------IQYLKIVTGTVDYTRPGAEYLVDGSKIHCS-----------HDKP 122
            :.|||||||::..       ::::::....|. |.|  :.:.:.:.:.|:           |..|
  Fly   184 RHILTAAHCVQGEGVRDRQGLKHVRLGEFNVK-TEP--DCIEEPNYLSCADAALDIAYEKIHVHP 245

  Fly   123 AY-------HNDIALIHTAKPIVYDDLTQPIKLASKGSLPKV---GDKLTLTGWGSTKTWGRYST 177
            .|       :||||:|....|:.:.....||.|.:| |.|..   |...:::|||.|..:.:|..
  Fly   246 EYKEFSNYKYNDIAIIRLKHPVSFTHFVMPICLPNK-SEPLTLAEGQMFSVSGWGRTDLFNKYFI 309

  Fly   178 QLQ-----KIDLNYIDHDNCQS-----RVRNANWLSEGHVCTFTQEGEGSCHGDSGGPLV----- 227
            .:.     |:.:.|:.::||..     .||    |....:|...:..:.:|.|||||||:
  Fly   310 NIHSPIKLKLRIPYVSNENCTKILEGFGVR----LGPKQICAGGEFAKDTCAGDSGGPLMYFDRQ 370

  Fly   228 DANQTLVGVVNWG-EACAI-GYPDVFGSVAYYHDWIEQMM 265
            .:.....|||::| ..|.: |.|.|:.:||.|.|||:.::
  Fly   371 HSRWVAYGVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	67/264 (25%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	68/265 (26%)
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	67/264 (25%)
		Tryp_SPc	150..409	CDD:238113	68/266 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010