DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and CG31326

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	71/249 - (28%)
Similarity:	110/249 - (44%)	Gaps:	29/249 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VIGGVDSPTGFAPYQVSIMNTFGEH----VCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYT 102
            :..|.....|..|:.|:|......:    :|||::|:...:|:||||...|.:.|......|...
  Fly   274 IFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLISTSTVLSAAHCFRAPGRDLPASRLAVSLG 338

  Fly   103 RPGAEYLVDGS-------KIHCSHD-KPAYHNDIALIHTAKPIVYDDLTQPIKL---ASKGSLPK 156
            |.......||.       .||.:.. |.....|:||:...:|:.|.|...||.|   :::..||:
  Fly   339 RNTLAIHSDGEFRGVSQLIIHENFQFKQFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLPQ 403

  Fly   157 VGDKLTLTGWGSTKTWGRYSTQLQKI-DLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHG 220
             |.|..:.|||..:| |..:|::.|: |||.:...||...:.:. .:....:|. .:.|.|.|..
  Fly   404 -GLKSYVAGWGPDET-GTGNTEVSKVTDLNIVSEANCALELPHV-LVQPSSLCA-KKTGAGPCAS 464

  Fly   221 DSGGPLVDANQ---TLVGVVNWG------EACAIGYPDVFGSVAYYHDWIEQMM 265
            |.||||:...|   .|.||::.|      ..|.:..|.||..||.:.:|:.|.|
  Fly   465 DGGGPLMLREQDVWVLRGVISGGVINEKENTCELSKPSVFTDVAKHIEWVRQKM 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	68/243 (28%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	69/245 (28%)
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	69/243 (28%)
		Tryp_SPc	277..514	CDD:214473	68/240 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436922
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940