Protein Alignment CG5246 and PRSS57

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 73/260 - (28%)
• Similarity: 108/260 - (41%)
• Gaps: 58/260 - (22%)

  Fly    36 VKPE-----TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIV 95
            |||.     .::|||.:......||..|: ...|:|.|||.::..:|:::||||    ..:..:.
Human    23 VKPPAGSWGAQIIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHC----FSHRDLR 82

  Fly    96 TGTVDYTRPGAEYL-----------VDGSKIHCSHDKPAYH-----NDIALIHTAKPIVYDD--- 141
            ||.|..   ||..|           :|....|     |.||     |||.|:......|...
Human    83 TGLVVL---GAHVLSTAEPTQQVFGIDALTTH-----PDYHPMTHANDICLLRLNGSAVLGPAVG 139

  Fly   142 -LTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEG 205
             |..|.:.|..   |..|.:..:.|||....:......|.:..:..:|.|.|     |::|  :|
Human   140 LLRPPGRRARP---PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVC-----NSSW--KG 194

  Fly   206 H-----VCTFTQEG--EGSCHGDSGGPLVDANQTLVGVVNW-GEACA-IGYPDVFGSVAYYHDWI 261
            |     :||.:.:.  .|.|..|||||||..|:. .|:|:: |..|. ...|||:..|:.:..||
Human   195 HLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRA-HGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258

  Fly   262  261
            Human   259  258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	70/249 (28%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	68/247 (28%)