Protein Alignment CG5246 and KLK2

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 69/246 - (28%)
• Similarity: 121/246 - (49%)
• Gaps: 35/246 - (14%)

  Fly    39 ETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTR 103
            ::|::||.:......|:||::.:....| |||.::.|||:||||||::   :..::..|..:...
Human    22 QSRIVGGWECEKHSQPWQVAVYSHGWAH-CGGVLVHPQWVLTAAHCLK---KNSQVWLGRHNLFE 82

  Fly   104 PGAEYLVDGSKIHCSHD--KPAYH----------------NDIALIHTAKPIVYDDLTQPIKLAS 150
            |..    .|.::..||.  .|.|:                :|:.|:..::|....|:.:.:.|.:
Human    83 PED----TGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143

  Fly   151 KGSLPKVGDKLTLTGWGSTKTWGRYSTQ-LQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQE 213
            :.  |.:|.....:||||.:.......: ||.:.|:.:.:|.| :|..:.. ::|..:|. ....
Human   144 QE--PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMC-ARAYSEK-VTEFMLCAGLWTG 204

  Fly   214 GEGSCHGDSGGPLVDANQTLVGVVNWG-EACAI-GYPDVFGSVAYYHDWIE 262
            |:.:|.|||||||| .|..|.|:.:|| |.||: ..|.|:..|.:|..||:
Human   205 GKDTCGGDSGGPLV-CNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	68/243 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	68/243 (28%)