Protein Alignment CG5246 and PRSS41

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 81/287 - (28%)
• Similarity: 127/287 - (44%)
• Gaps: 57/287 - (19%)

  Fly    16 CSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILT 80
            |.|:|   .....|:...||.:....|.|||:|..|..|:|.| :.....|.||||:::.:|:|:
Human    48 CPAES---QEEELLSEACGHREIHALVAGGVESARGRWPWQAS-LRLRRRHRCGGSLLSRRWVLS 108

  Fly    81 AAHCM-------EWPIQYLKIVTGTVDYTRP--------GAEYLVDGSKIHCSHDKP----AYHN 126
            ||||.       ||.:|..::.      :||        .:.|.|....::     |    ...|
Human   109 AAHCFQKHYYPSEWTVQLGELT------SRPTPWNLRAYSSRYKVQDIIVN-----PDALGVLRN 162

  Fly   127 DIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGR-----YSTQLQKIDLNY 186
            ||||:..|..:.|:...|||.:.|............:||||.....|.     |:  |::..:..
Human   163 DIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYN--LREAQVTI 225

  Fly   187 IDHDNC-----QSRVRNANWLSEGHVCTFTQEGE-GSCHGDSGGPLV---DANQTLVGVVNWGEA 242
            :::..|     |...|:..|  :...|...::|. .:|.||||||||   |.....||:|:||..
Human   226 LNNTRCNYLFEQPSSRSMIW--DSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMD 288

  Fly   243 CAIGYPD---VFGSVAYYHDWIEQMMT 266
            |  |.|:   |:.:::.|..||.::|:
Human   289 C--GQPNRPGVYTNISVYFHWIRRVMS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	74/256 (29%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	74/257 (29%)