Protein Alignment CG5246 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 78/238 - (32%)
• Similarity: 115/238 - (48%)
• Gaps: 21/238 - (8%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEW---PIQYLKIVTGTVDY 101
            ||::||..:..|..|:|||:.....||.||..::|.:|:|:||||.:.   |.|:...: ||...
Human   859 TRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFL-GTPFL 922

  Fly   102 TRPGAEYLVDGSKIHCSHDKPAYH-----NDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKL 161
            :  |||..::  ::...:..|.|:     .|:||:..|.|:....|.:||.|......|..|.:.
Human   923 S--GAEGQLE--RVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRC 983

  Fly   162 TLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGGP 225
            .:|||||.:..|..:.||||..:..:....|: |..... :|...:|. |.|.|..||.||:|||
Human   984 VITGWGSVREGGSMARQLQKAAVRLLSEQTCR-RFYPVQ-ISSRMLCAGFPQGGVDSCSGDAGGP 1046

  Fly   226 LV----DANQTLVGVVNWGEACA-IGYPDVFGSVAYYHDWIEQ 263
            |.    .....|.||.:||..|. ..:|.|:..||....||.|
Human  1047 LACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQ 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	75/234 (32%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113
		Pneumo_att_G	<717..>867	CDD:114270	4/7 (57%)
		Tryp_SPc	861..1087	CDD:238113	73/232 (31%)