Protein Alignment CG5246 and KLK3

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 73/250 - (29%)
• Similarity: 115/250 - (46%)
• Gaps: 45/250 - (18%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTRP 104
            :|::||.:......|:||.:.:. |..||||.::.|||:||||||:.   ....|:.|......|
Human    23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIR---NKSVILLGRHSLFHP 83

  Fly   105 ---GAEYLVDGSKIHCSHDKPAYHN-----------DIALIHTAKPIVYDDLTQPIKLASKGSLP 155
               |..:.|..|..|..:|.....|           |:.|:..::|....|..:.:.|.::.  |
Human    84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE--P 146

  Fly   156 KVGDKLTLTGWGSTKTWGRYST--QLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQ------ 212
            .:|.....:||||.:. ..:.|  :||.:||:.|.:|.|          ::.|....|:
Human   147 ALGTTCYASGWGSIEP-EEFLTPKKLQCVDLHVISNDVC----------AQVHPQKVTKFMLCAG 200

  Fly   213 ---EGEGSCHGDSGGPLVDANQTLVGVVNWG-EACAI-GYPDVFGSVAYYHDWIE 262
               .|:.:|.|||||||| .|..|.|:.:|| |.||: ..|.::..|.:|..||:
Human   201 RWTGGKSTCSGDSGGPLV-CNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	72/247 (29%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	72/247 (29%)