Protein Alignment CG5246 and TMPRSS7

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001382436.1
• Gene: TMPRSS7 / 344805
• HGNCID: 30846
• Length: 843
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 76/267 - (28%)
• Similarity: 114/267 - (42%)
• Gaps: 44/267 - (16%)

  Fly    16 CSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILT 80
            ||..|..:|                |:|||.|:..|..|:||| ::..|...||.|:|:.:|:|:
Human   596 CSRSSSALH----------------RIIGGTDTLEGGWPWQVS-LHFVGSAYCGASVISREWLLS 643

  Fly    81 AAHCME---------WPIQYLKIVTGTVDYTRPGAEYLVDGSKIHCSHDKPAYHNDIALIH--TA 134
            ||||..         |.......|.|...:..|....:|     |..::...:..||||:.  .|
Human   644 AAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVV-----HEYYNSQTFDYDIALLQLSIA 703

  Fly   135 KPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGST-KTWGRYSTQLQKIDLNYIDHDNCQSRVRN 198
            .|.....|.|||.:...|...:.|:|..:||||.. :...:.|..||:.::..||...|   |..
Human   704 WPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLC---VST 765

  Fly   199 ANWLSEGHVCTFTQEGE-GSCHGDSGGPL-----VDANQTLVGVVNWGEACA-IGYPDVFGSVAY 256
            ...::...:|.....|: .:|.|||||||     .|....|.|:|:||.... ..:|.|:..|:.
Human   766 YGIITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSN 830

  Fly   257 YHDWIEQ 263
            :..||.:
Human   831 FVPWIHK 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	71/239 (30%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..67
		SEA	108..207	CDD:460188
		CUB	247..359	CDD:238001
		LDLa	484..518	CDD:238060
		LDLa	559..594	CDD:238060
		Tryp_SPc	605..835	CDD:214473	70/238 (29%)