DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and psh

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_573297.1	Gene:	psh / 32832	FlyBaseID:	FBgn0030926	Length:	394	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	79/270 - (29%)
Similarity:	121/270 - (44%)	Gaps:	40/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KIHRRHQL---NHHLGHVKPETRVIGGVDSPTGFAPYQVSI-MNTFG-EHVCGGSIIAPQWILTA 81
            ||..|.|.   |..:.|      ::||.....|..|:..:| ..||| :..||||:||.:::|||
  Fly   127 KIRERKQQRSGNQLVIH------IVGGYPVDPGVYPHMAAIGYITFGTDFRCGGSLIASRFVLTA 185

  Fly    82 AHCMEWPIQYLKIV-TGTVDYTRPGAEY---LVDGSKIHCSHDKPAY----HNDIALIHTAKPIV 138
            |||:.........| .|.|:...|...|   ::...|||     |.|    :||||::...:.:|
  Fly   186 AHCVNTDANTPAFVRLGAVNIENPDHSYQDIVIRSVKIH-----PQYVGNKYNDIAILELERDVV 245

  Fly   139 YDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQ-LQKIDLNYIDHDNCQ----SRVRN 198
            ..|..:|..|.:..:.|....|..:.|||......|..:: |.:..|..:..|.|.    .:..:
  Fly   246 ETDNIRPACLHTDATDPPSNSKFFVAGWGVLNVTTRARSKILLRAGLELVPLDQCNISYAEQPGS 310

  Fly   199 ANWLSEGHV----CTFTQE-GEGSCHGDSGGPLV------DANQTLVGVVNWGEACAIGYPDVFG 252
            ...|.:|.:    |...|: ...:|.|||||||:      |...|::||::.|..||...|.::.
  Fly   311 IRLLKQGVIDSLLCAIDQKLIADACKGDSGGPLIHELNVEDGMYTIMGVISSGFGCATVTPGLYT 375

  Fly   253 SVAYYHDWIE 262
            .|:.|.|:||
  Fly   376 RVSSYLDFIE 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	71/245 (29%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	73/247 (30%)
psh	NP_573297.1	CLIP	30..79	CDD:197829
		Tryp_SPc	143..384	CDD:214473	72/251 (29%)
		Tryp_SPc	144..387	CDD:238113	73/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437643
Domainoid	1	1.000	70	1.000	Domainoid score	I6224
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940