DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and spirit

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	74/253 - (29%)
Similarity:	122/253 - (48%)	Gaps:	36/253 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VIGGVDSPTGFAPYQVSI--MNTFGEHV---CGGSIIAPQWILTAAHCMEW---PIQYLKIVTGT 98
            |:||:.:.....|:..::  .:.|.:.:   |||::||..::||||||.:.   |...:::....
  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDN 196

  Fly    99 VDYTRPGAEYLVDGSKIHCSHDKPAYHNDIALIH---TAKPIVYDDLTQPIKLASKGSLPKVGDK 160
            :..|. |.:..:....||..:.....:|||||:.   .|||        .:|.....:..:|.:.
  Fly   197 LTLTE-GEDISIRRVIIHPDYSASTAYNDIALLELETAAKP--------ELKPTCIWTQKEVTNT 252

  Fly   161 L-TLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEG----HVCTFTQEGE-GSCH 219
            | |..|:|.|...|..|.||.|:.|..:.::.||...:. :.|::|    .:|.....|| .:|.
  Fly   253 LVTAIGYGQTSFAGLSSAQLLKVPLKSVSNEECQHHYQK-DQLAQGVLGTQMCAGDITGERDTCQ 316

  Fly   220 GDSGGPLVDANQTL---VGVVNWGEACAIGYPDVFGSVAYYHDWIE------QMMTDA 268
            |||||||:..:..|   ||:.:.|:.||.|.|.|:..|:.:.||||      |.:|:|
  Fly   317 GDSGGPLLMQDGLLGYVVGITSLGQGCASGPPSVYTRVSSFVDWIEGIVWPAQQVTNA 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	68/238 (29%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	71/246 (29%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	71/241 (29%)
		Tryp_SPc	132..361	CDD:214473	68/238 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940