Protein Alignment CG5246 and Prss22

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 290
• Identity: 90/290 - (31%)
• Similarity: 138/290 - (47%)
• Gaps: 42/290 - (14%)

  Fly     2 KCLVLISVLVILSQCSAKSVK----IHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNT 62
            :.|:|:.:|...:..||.:::    ..:..|||          ||:||.||.....|:.|||:..
  Rat    16 RTLILLVLLTSTATVSAANIRGSPDCGKPQQLN----------RVVGGEDSADAQWPWIVSILKN 70

  Fly    63 FGEHVCGGSIIAPQWILTAAHC----MEWPIQYLKIVTGTVDYTRPGAEYLVDGSKIHCSHDKPA 123
             |.|.|.||::..:|:::||||    |:.|..| .::.|......||......|......|  |.
  Rat    71 -GSHHCAGSLLTNRWVVSAAHCFSSNMDKPSPY-SVLLGAWKLGNPGPRSQKVGIASVLPH--PR 131

  Fly   124 Y------HNDIALIHTAKPIVYDDLTQPIKLA-SKGSLPKVGDKLTLTGWGSTK---TWGRYSTQ 178
            |      |.||||:...:||.:.:...||.|. |...||. .....:.||||.:   ...|..|
  Rat   132 YSRKEGTHADIALVRLERPIQFSERILPICLPDSSVHLPP-NTNCWIAGWGSIQDGVPLPRPQT- 194

  Fly   179 LQKIDLNYIDHDNCQS---RVRNANWLSEGHVCTFTQEGE-GSCHGDSGGPL---VDANQTLVGV 236
            |||:.:..||.:.|:|   |......::|..:|....||: .:|.|||||||   ||.:..|.|:
  Rat   195 LQKLKVPIIDPELCKSLYWRGAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQVDDHWLLTGI 259

  Fly   237 VNWGEACA-IGYPDVFGSVAYYHDWIEQMM 265
            ::|||.|| ...|.|:.|:..:..|:::::
  Rat   260 ISWGEGCAERNRPGVYTSLLAHRPWVQRIV 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	81/242 (33%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	81/243 (33%)