Protein Alignment CG5246 and GZMK

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 74/259 - (28%)
• Similarity: 110/259 - (42%)
• Gaps: 32/259 - (12%)

  Fly    32 HLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVT 96
            ::.||.....:|||.:......|:..||... |.|||||.:|.|||:||||||     || :...
Human    17 YMTHVCFNMEIIGGKEVSPHSRPFMASIQYG-GHHVCGGVLIDPQWVLTAAHC-----QY-RFTK 74

  Fly    97 GTVDYTRPGAEYLVDGSKIHCSHD--------------KPAYHNDIALIHTAKPIVYDDLTQPIK 147
            |.......||..|   ||...|..              .....|||.|:........:...:.:.
Human    75 GQSPTVVLGAHSL---SKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLH 136

  Fly   148 LASKGSLPKVGDKLTLTGWGSTKTWG-RYSTQLQKIDLNYIDHDNC--QSRVRNANWLSEGHVCT 209
            :.||.|| :.|.|..:||||:|.... |.|..|:::.:..:....|  ||......::::..||.
Human   137 IRSKTSL-RSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 200

  Fly   210 FTQEGE-GSCHGDSGGPLVDANQTLVGVVNWGEACAIG-YPDVFGSVA-YYHDWIEQMMTDAGT 270
            ...:|: .||.|||||||: .......:|:.|..|.:. .|.::..:. .|..||:..:....|
Human   201 GDAKGQKDSCKGDSGGPLI-CKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHT 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	71/240 (30%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	71/241 (29%)