Protein Alignment CG5246 and KLK9

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_036447.1
• Gene: KLK9 / 284366
• HGNCID: 6370
• Length: 250
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 82/294 - (27%)
• Similarity: 130/294 - (44%)
• Gaps: 75/294 - (25%)

  Fly     1 MKCLVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGE 65
            ||..:|.::|.:|:                   ||...:||.||..:......|:|..:.
Human     1 MKLGLLCALLSLLA-------------------GHGWADTRAIGAEECRPNSQPWQAGLF----- 41

  Fly    66 HV----CGGSIIAPQWILTAAHC----------------MEWPIQYLKIVTGTVDYTRPGAEYLV 110
            |:    ||.::|:.:|:||||||                .|.|.|..::   |..:..||.
Human    42 HLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRV---TDFFPHPGF---- 99

  Fly   111 DGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKT-WGR 174
              :|...::|   :::||.||...:........||:.|:.....|  |.:..::|||:..: ...
Human   100 --NKDLSAND---HNDDIMLIRLPRQARLSPAVQPLNLSQTCVSP--GMQCLISGWGAVSSPKAL 157

  Fly   175 YSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHV-----CTFTQE-GEGSCHGDSGGPLVDANQTL 233
            :...||..:::.:::..|       :|...||:     |....| |.|||.|||||||| .|.||
Human   158 FPVTLQCANISILENKLC-------HWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLV-CNGTL 214

  Fly   234 VGVVNWG-EACA-IGYPDVFGSVAYYHDWIEQMM 265
            .|||:.| |.|: ...|.|:.||.:|.|||:::|
Human   215 AGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIM 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	72/249 (29%)
KLK9	NP_036447.1	Tryp_SPc	24..247	CDD:238113	72/249 (29%)