DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and Sp212

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	58/249 - (23%)
Similarity:	118/249 - (47%)	Gaps:	39/249 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VIGGVDSPTGFAPYQVSIMNTFGEHV------CGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVD 100
            ::.|.:.|.|..|:..::   :.:.|      |.||:|:...:::||||:....:. ::|.|...
  Fly   277 IVRGNEFPRGQYPWLSAV---YHKEVRALAFKCRGSLISSSIVISAAHCVHRMTED-RVVVGLGR 337

  Fly   101 YTRPGAEYLVDGSKI--------HCSHDKPAYHN-DIALIHTAKPIVYDDLTQPIKLASKGSLPK 156
            |...  :|..||:::        |..::..:|.: |||||...:|:.::|:..||.:.:..:...
  Fly   338 YDLD--DYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRT 400

  Fly   157 VGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANW----LSEGHVCTFTQEGEGS 217
            |.....:.|||..:...|  ||..::    ::.:.....|..:.|    ::|..:|...::|.|.
  Fly   401 VSTTGFIAGWGRDEDSSR--TQYPRV----VEAEIASPTVCASTWRGTMVTERSLCAGNRDGSGP 459

  Fly   218 CHGDSGGPLV--DANQTLV-GVVNWGE-----ACAIGYPDVFGSVAYYHDWIEQ 263
            |.|||||.|:  ..::.|: |:|:.||     .|.:....::..::.:.:||.:
  Fly   460 CVGDSGGGLMVKQGDRWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISE 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	56/245 (23%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	58/247 (23%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	58/249 (23%)
		Tryp_SPc	277..511	CDD:214473	56/245 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930