Protein Alignment CG5246 and KLK13

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 82/291 - (28%)
• Similarity: 130/291 - (44%)
• Gaps: 67/291 - (23%)

  Fly     4 LVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGF-----------APYQV 57
            ||:.|:.:.||                   |.|..|:..:...:..:||           .|:|.
Human     6 LVIASLTLALS-------------------GGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQA 51

  Fly    58 SIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTG--------------TVDYTRPGAEY 108
            ::: ..|..:|||.::.|:|:||||||::   :.||:..|              .|.::.|..||
Human    52 ALL-VQGRLLCGGVLVHPKWVLTAAHCLK---EGLKVYLGKHALGRVEAGEQVREVVHSIPHPEY 112

  Fly   109 LVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKT-W 172
              ..|..|.:||     :||.|:....|:......|.:.|:....|.. |....::|||:|.: .
Human   113 --RRSPTHLNHD-----HDIMLLELQSPVQLTGYIQTLPLSHNNRLTP-GTTCRVSGWGTTTSPQ 169

  Fly   173 GRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQE-GEGSCHGDSGGPLVDANQTLVGV 236
            ..|...||..::.....:.|  |......:::..:|..|:| |:.||.|||||||| .|:||.|:
Human   170 VNYPKTLQCANIQLRSDEEC--RQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLV-CNRTLYGI 231

  Fly   237 VNWGE-ACAIGYPD---VFGSVAYYHDWIEQ 263
            |:||: .|  |.||   |:..|:.|..||.:
Human   232 VSWGDFPC--GQPDRPGVYTRVSRYVLWIRE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	74/251 (29%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	72/240 (30%)