DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5246 and Ovch2

DIOPT Version :9

Sequence 1:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_766496.2	Gene:	Ovch2 / 244199	MGIID:	3045251	Length:	609	Species:	Mus musculus

Alignment Length:	292	Identity:	87/292 - (29%)
Similarity:	135/292 - (46%)	Gaps:	39/292 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPE--------TRVIGGVDSPTGFAPYQVSIM 60
            |:||..:|.|.|..::::...|.......|  |||:        :|::||.....|..|:|||:.
Mouse     8 LILILGMVCLEQGHSETLSSIRNPDCGQSL--VKPQPQNYFSLFSRIVGGSQVEKGSYPWQVSLK 70

  Fly    61 NTFGEHVCGGSIIAPQWILTAAHCM--EWPIQYLKIVTGTVDYTR--PGAEYL-VDGSKIH--CS 118
            .. .:|:|||:||:.||::||||||  ......|.:..|..|.::  ||.:.| ::...||  .|
Mouse    71 QK-QKHICGGTIISSQWVITAAHCMANRNIALTLNVTAGEHDLSQAEPGEQTLAIETIIIHPQFS 134

  Fly   119 HDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKID 183
            ..||..: ||||:..|....:....:|:.|...|.....|...|..|||.....||....||:::
Mouse   135 TRKPMIY-DIALLKMAGTFQFGQFVRPVCLPEPGEHFNAGFICTTAGWGRLSEGGRLPQVLQQVN 198

  Fly   184 LNYIDHDNCQS---RVRNANWLSEGHVCTFTQE-GEGSCHGDSGGPLVDANQ----TLVGVVNWG 240
            |..:..:.|::   .::|. ...:..:||.:.: |..:|.|||||.|:..|:    ||.||.:||
Mouse   199 LPILTQEECEAVLLTLKNP-ITGKTFLCTGSPDGGRDACQGDSGGSLMCQNRKGAWTLAGVTSWG 262

  Fly   241 EACA-----------IGYPDVFGSVAYYHDWI 261
            ..|.           .|.|.:|..:.....||
Mouse   263 LGCGRSWRNNARKKEQGSPGIFTDLRRVLPWI 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	74/245 (30%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	75/246 (30%)
Ovch2	NP_766496.2	Tryp_SPc	51..294	CDD:214473	74/245 (30%)
		Tryp_SPc	52..297	CDD:238113	75/246 (30%)
		CUB	317..420	CDD:238001
		CUB	431..542	CDD:238001
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	580..609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910