Protein Alignment CG5246 and TPSD1

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_036349.1
• Gene: TPSD1 / 23430
• HGNCID: 14118
• Length: 242
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 60/224 - (26%)
• Similarity: 95/224 - (42%)
• Gaps: 47/224 - (20%)

  Fly    34 GHVKPETRVIGGVDSPTGFAPYQVS--IMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVT 96
            |....:|.::||.::|....|:|||  :...:..|.||||:|.|||:||||||:|..|:.|..:.
Human    30 GQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALR 94

  Fly    97 GTV--------DYTRPGAEYLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLAS--- 150
            ..:        |...|.:..:|              |....:|.|...|...:|.:|:.::|
Human    95 VQLREQHLYYQDQLLPVSRIIV--------------HPQFYIIQTGADIALLELEEPVNISSHIH 145

  Fly   151 KGSLPKVGDKLT------LTGWGSTKTWGRYST--QLQKIDLNYIDHDNCQSRVRNANWLSEGH- 206
            ..:||...:...      :||||..........  .|:::::..:::..|.:.....  |..||
Human   146 TVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTG--LHTGHS 208

  Fly   207 --------VCTFTQEGEGSCHGDSGGPLV 227
                    :|. ..|...||.||||||||
Human   209 FQIVRDDMLCA-GSENHDSCQGDSGGPLV 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	58/216 (27%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	58/216 (27%)