Protein Alignment CG5246 and F9

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 77/242 - (31%)
• Similarity: 125/242 - (51%)
• Gaps: 28/242 - (11%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTG-----TV 99
            |||:||.|:..|..|:|| ::|...:..|||||:..:||:|||||:|..:: :.:|.|     ..
Human   225 TRVVGGEDAKPGQFPWQV-VLNGKVDAFCGGSIVNEKWIVTAAHCVETGVK-ITVVAGEHNIEET 287

  Fly   100 DYTRPGAEYLVDGSKIHCSHDKPA----YHNDIALIHTAKPIVYDDLTQPIKLASK---GSLPKV 157
            ::|......:    :|...|:..|    |::||||:...:|:|.:....||.:|.|   ....|.
Human   288 EHTEQKRNVI----RIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKF 348

  Fly   158 GDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANW-LSEGHVCT-FTQEGEGSCHG 220
            |... ::|||.....||.:..||.:.:..:|...|   :|:..: :.....|. |.:.|..||.|
Human   349 GSGY-VSGWGRVFHKGRSALVLQYLRVPLVDRATC---LRSTKFTIYNNMFCAGFHEGGRDSCQG 409

  Fly   221 DSGGP---LVDANQTLVGVVNWGEACAI-GYPDVFGSVAYYHDWIEQ 263
            |||||   .|:....|.|:::|||.||: |...::..|:.|.:||::
Human   410 DSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	75/238 (32%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	75/240 (31%)