Protein Alignment CG5246 and PRSS55

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 83/238 - (34%)
• Similarity: 120/238 - (50%)
• Gaps: 18/238 - (7%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCM---EWPIQYLKIVTGTVDY 101
            :|:.||:::..|..|:|||| ....|..|||||:...||||||||:   |...:.|.:|.||.|.
Human    90 SRITGGMEAEVGEFPWQVSI-QARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDL 153

  Fly   102 TRPGAEYLVDGSKI-HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTG 165
            |.|..|.....|.| |....:....|||||:..|.||..|||..||.|.::.. |....:..:.|
Human   154 TSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPG-PATWRECWVAG 217

  Fly   166 WGSTKTWGRYS--TQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGGPLV 227
            ||.|....:.|  |.|.|..:..:|.:.|......   |::..:|. :..|...:|.||||||||
Human   218 WGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK---LTKNMLCAGYKNESYDACKGDSGGPLV 279

  Fly   228 DANQT-----LVGVVNWGEACA-IGYPDVFGSVAYYHDWIEQM 264
            ...:.     .||:::||::|. ...|.::.|:..|:.|||::
Human   280 CTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	81/233 (35%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	82/234 (35%)