Protein Alignment CG5246 and ELANE

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001963.1
• Gene: ELANE / 1991
• HGNCID: 3309
• Length: 267
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 69/271 - (25%)
• Similarity: 118/271 - (43%)
• Gaps: 37/271 - (13%)

  Fly     1 MKCLVLISVLVILSQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTFGE 65
            :.||.|..||..|.                  ||.....:.::||..:.....|:.|| :...|.
Human     7 LACLFLACVLPALL------------------LGGTALASEIVGGRRARPHAWPFMVS-LQLRGG 52

  Fly    66 HVCGGSIIAPQWILTAAHCM-EWPIQYLKIVTGTVDYTR--PGAEYLVDGSKIHCSHDKPAYHND 127
            |.||.::|||.::::||||: ...::.:::|.|..:.:|  |..:...........:|.....||
Human    53 HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND 117

  Fly   128 IALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNC 192
            |.::........:...|..:|.::|.....|.:....|||........::.||::::..:
Human   118 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV----- 177

  Fly   193 QSRVRNANWLSEGHVCTFTQEGE-GSCHGDSGGPLVDANQTLVGVVNWGE-ACAIG-YPDVFGSV 254
            .|..|.:|      |||..:..: |.|.||||.||| .|..:.|:.::.. .||.| |||.|..|
Human   178 TSLCRRSN------VCTLVRGRQAGVCFGDSGSPLV-CNGLIHGIASFVRGGCASGLYPDAFAPV 235

  Fly   255 AYYHDWIEQMM 265
            |.:.:||:.::
Human   236 AQFVNWIDSII 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	61/226 (27%)
ELANE	NP_001963.1	Tryp_SPc	30..245	CDD:238113	61/227 (27%)