Protein Alignment CG5246 and CFD

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 67/237 - (28%)
• Similarity: 109/237 - (45%)
• Gaps: 15/237 - (6%)

  Fly    38 PETRVIGGVDSPTGFAPYQVSI-MNTFGEHVCGGSIIAPQWILTAAHCMEWPIQ-YLKIVTGTVD 100
            |..|::||.::.....||..|: :|  |.|:|||.::|.||:|:||||:|.... .::::.|...
Human    29 PRGRILGGREAEAHARPYMASVQLN--GAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 91

  Fly   101 YTRPGAE---YLVDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDLTQPI--KLASKGSLPKVGDK 160
            .::|...   |.|..:..|.........:|:.|:..::........:|:  :...:...|  |..
Human    92 LSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP--GTL 154

  Fly   161 LTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGDSGGP 225
            ..:.|||.....||....||.:.|..:|...|..|..:...::|..:|..:...: ||.||||||
Human   155 CDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRD-SCKGDSGGP 218

  Fly   226 LVDANQTLVGVVNWG-EACA-IGYPDVFGSVAYYHDWIEQMM 265
            || ....|.|||..| ..|. ...|.::..||.|..||:.::
Human   219 LV-CGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	65/229 (28%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	65/230 (28%)