Protein Alignment CG5246 and CTSG

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_011534801.1
• Gene: CTSG / 1511
• HGNCID: 2532
• Length: 269
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 61/232 - (26%)
• Similarity: 110/232 - (47%)
• Gaps: 18/232 - (7%)

  Fly    42 VIGGVDSPTGFAPYQ--VSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTR- 103
            :|||.:|.....||.  :.|.:..|:..|||.::...::||||||  |. ..:.:..|..:..|
Human    35 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHC--WG-SNINVTLGAHNIQRR 96

  Fly   104 -PGAEYLVDGSKI-HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKL--ASKGSLPKVGDKLTLT 164
             ...:::.....| |..:::....|||.|:..::.:..:....|:.|  |.:|..|  |...|:.
Human    97 ENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRP--GTLCTVA 159

  Fly   165 GWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCT-FTQEGEGSCHGDSGGPLVD 228
            |||.. :..|.:..|:::.|. :..|....|: ..::.....:|. ..:|.:.:..|||||||:
Human   160 GWGRV-SMRRGTDTLREVQLR-VQRDRQCLRI-FGSYDPRRQICVGDRRERKAAFKGDSGGPLL- 220

  Fly   229 ANQTLVGVVNWGEACAIGYPDVFGSVAYYHDWIEQMM 265
            .|....|:|::|::..:. |:||..|:.:..||...|
Human   221 CNNVAHGIVSYGKSSGVP-PEVFTRVSSFLPWIRTTM 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	60/228 (26%)
CTSG	XP_011534801.1	Tryp_SPc	35..255	CDD:238113	60/229 (26%)