Protein Alignment CG5246 and CTRB1

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 72/243 - (29%)
• Similarity: 114/243 - (46%)
• Gaps: 31/243 - (12%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTV----D 100
            :|::.|.|:..|..|:|||:.:..|.|.||||:|:..|::|||||        .:.|..|    :
Human    32 SRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--------GVRTSDVVVAGE 88

  Fly   101 YTRPGAEYLVDGSKIHCSHDKPAY-----HNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDK 160
            :.:...|..:...||......|.:     :|||.|:..|.|..:......:.|.|.......|..
Human    89 FDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTL 153

  Fly   161 LTLTGWGSTK-TWGRYSTQLQKIDLNYIDHDNCQSRVRNANW---LSEGHVCTFTQEGEGSCHGD 221
            ...||||.|| ...:...:||:..|..:.:..|:.     :|   :::..:|. ...|..||.||
Human   154 CATTGWGKTKYNANKTPDKLQQAALPLLSNAECKK-----SWGRRITDVMICA-GASGVSSCMGD 212

  Fly   222 SGGPLV---DANQTLVGVVNWG-EACAIGYPDVFGSVAYYHDWIEQMM 265
            ||||||   |...||||:|:|| :.|:...|.|:..|.....|:::::
Human   213 SGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKIL 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	71/237 (30%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	71/238 (30%)