Protein Alignment CG5246 and Cfd

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 273
• Identity: 70/273 - (25%)
• Similarity: 116/273 - (42%)
• Gaps: 30/273 - (10%)

  Fly     1 MKCLVLISVLVIL--SQCSAKSVKIHRRHQLNHHLGHVKPETRVIGGVDSPTGFAPYQVSIMNTF 63
            |...|....||||  :.|:|                  :|..|::||.::.....||..|: ...
Mouse     1 MHSSVYFVALVILGAAVCAA------------------QPRGRILGGQEAAAHARPYMASV-QVN 46

  Fly    64 GEHVCGGSIIAPQWILTAAHCMEWPI--QYLKIVTGTVDYTRPGAE---YLVDGSKIHCSHDKPA 123
            |.|||||:::..||:|:|||||:...  ..::::.|....:.|...   |.|.....|......:
Mouse    47 GTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDS 111

  Fly   124 YHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYID 188
            ..:|:.|...::........:|:.|..:....:.|....:.|||.....||....|.::.::.::
Mouse   112 LEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMN 176

  Fly   189 HDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGDSGGPLVDANQTLVGVVNWG-EACAIG-YPDVF 251
            ...|..|..:...::...:|..:...: :|.||||.||| ....:.|||.|| ..|..| .|.|:
Mouse   177 RTTCNLRTYHDGVVTINMMCAESNRRD-TCRGDSGSPLV-CGDAVEGVVTWGSRVCGNGKKPGVY 239

  Fly   252 GSVAYYHDWIEQM 264
            ..|:.|..|||.:
Mouse   240 TRVSSYRMWIENI 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	59/227 (26%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	60/228 (26%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)