Protein Alignment CG5246 and PRSS21

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 80/261 - (30%)
• Similarity: 125/261 - (47%)
• Gaps: 42/261 - (16%)

  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCME----------WPIQYLKI 94
            :|::||.|:..|..|:|.| :..:..||||.|:::.:|.||||||.|          |.:|:.::
Human    40 SRIVGGEDAELGRWPWQGS-LRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQL 103

  Fly    95 VTG------TVDYTRPGAEYLVDGSKIHCSHDKPAYHN----DIALIHTAKPIVYDDLTQPIKL- 148
            .:.      ...|||    |.|  |.|:.|   |.|..    ||||:..:.|:.|....|||.|
Human   104 TSMPSFWSLQAYYTR----YFV--SNIYLS---PRYLGNSPYDIALVKLSAPVTYTKHIQPICLQ 159

  Fly   149 ASKGSLPKVGDKLTLTGWGSTKTWGRYST--QLQKIDLNYIDHDNCQSRVRNANWLSE---GHVC 208
            ||........| ..:||||..|......:  .||::.:..|::..|.......::..:   ..||
Human   160 ASTFEFENRTD-CWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVC 223

  Fly   209 T-FTQEGEGSCHGDSGGPLVDANQTL---VGVVNWGEACA-IGYPDVFGSVAYYHDWIEQMMTDA 268
            . ..|.|:.:|.|||||||......|   :|||:||..|. ...|.|:.:::::.:||:::|..:
Human   224 AGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQS 288

  Fly   269 G 269
            |
Human   289 G 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	77/251 (31%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	77/251 (31%)