Protein Alignment CG5246 and tmprss6

DIOPT Version :10

• Sequence 1: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_004913946.2
• Gene: tmprss6 / 100489045
• XenbaseID: XB-GENE-1011573
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 245
• Identity: 81/245 - (33%)
• Similarity: 115/245 - (46%)
• Gaps: 31/245 - (12%)

  Fly    41 RVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLK-----IVTGTVD 100
            |::||..:..|..|:|.| :...|||:|||:::|.|||||||||.. |..|..     :..|.|.
 Frog   570 RLVGGTQAQEGEWPWQAS-LQVRGEHICGGTLVADQWILTAAHCFT-PESYASPEVWTVYLGKVR 632

  Fly   101 YTRPGAEYL---VDGSKIHCSHDKPAYHNDIALIHTAKPIVYDDL-------TQPIKLASKGSLP 155
            .:|...:.|   |....||..:|:.::..|:||      ::.|.|       .|||.|.|.....
 Frog   633 LSRSTQKELAFKVIRLVIHPFYDEDSHDYDVAL------VLLDHLVPLTSPHVQPICLPSSTHHF 691

  Fly   156 KVGDKLTLTGWGSTKTWGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEG-EGSCH 219
            ..|....:|||||.|..|..|..|||:|:..:..|.|....|..  :|...:|...::| :.:|.
 Frog   692 PTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTELYRYQ--ISPRMLCAGYRDGSKDACQ 754

  Fly   220 GDSGGPLV----DANQTLVGVVNWGEACAI-GYPDVFGSVAYYHDWIEQM 264
            ||||.|||    .......|:|:||..|.| .|..|:..:.....|||.:
 Frog   755 GDSGSPLVCKTASGRWFQAGLVSWGAGCGIPRYFGVYSRITRLVQWIESI 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	79/241 (33%)
tmprss6	XP_004913946.2	SEA	77..174	CDD:460188
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060
		Tryp_SPc	572..804	CDD:238113	80/241 (33%)