DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31266 and KLK4

DIOPT Version :9

Sequence 1:	NP_001138068.1	Gene:	CG31266 / 42071	FlyBaseID:	FBgn0051266	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_004908.4	Gene:	KLK4 / 9622	HGNCID:	6365	Length:	254	Species:	Homo sapiens

Alignment Length:	247	Identity:	67/247 - (27%)
Similarity:	107/247 - (43%)	Gaps:	46/247 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 RVIGGTTAAEGNWPWIASI--QNAYSYHLCGAIILDETWVLTAASCV-------AGLRPLNLLVV 106
            ::|.|...:..:.||.|::  :|..   .|..:::...|||:||.|.       .||..|.....
Human    30 QIINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQE 91

  Fly   107 TGTVDWWDLYAPYYTVSQIHV-HCNFDKPLYHNDIALLQLSSKIEFNDVTKNITLADIDELEEGD 170
            .|:         ....:.:.| |..:::||..||:.|::|...:..:|..::|::|. .....|:
Human    92 PGS---------QMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS-QCPTAGN 146

  Fly   171 KLTFAGWGSSEAMGTYGRYLQEASGTYLPVDACREKLQNQDDVDLGH---VCVQMDAGQG----- 227
            ....:|||.. |.|.....||..:.:.:..:.| .||.:    .|.|   .|    ||.|
Human   147 SCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVC-SKLYD----PLYHPSMFC----AGGGQDQKD 201

  Fly   228 ACHGDTGGPLI--DEQQRLVGIGNWGVPCGR-GYPDVYARTAFYHDWIRTTM 276
            :|:||:|||||  ...|.||..|.  .|||: |.|.||.....:.:||..|:
Human   202 SCNGDSGGPLICNGYLQGLVSFGK--APCGQVGVPGVYTNLCKFTEWIEKTV 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	51..272	CDD:214473	64/241 (27%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	66/243 (27%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	66/243 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920