DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31266 and Cfi

DIOPT Version :9

Sequence 1:	NP_001138068.1	Gene:	CG31266 / 42071	FlyBaseID:	FBgn0051266	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_077071.1	Gene:	Cfi / 79126	RGDID:	620429	Length:	604	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	86/302 - (28%)
Similarity:	119/302 - (39%)	Gaps:	77/302 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GPTEAMRMRGEPLPGLANIERHRSTEAVP-------------QGRVIGGTTAAEGNWPWIASIQN 71
            |.||......|.|....:.||.|....:|             :.||:||..|..|::||..:|::
  Rat   317 GETEIETEETEMLTPDMDTERKRIKSLLPKLSCGVKRNTHIRRKRVVGGKPAEMGDYPWQVAIKD 381

  Fly    72 AYSYHLCGAIILDETWVLTAASCVAGLRPLNLLVVTGTVDWW--DLYAPYYTVSQIHVHCNFDKP 134
            . ....||.|.:...|:||||.||...|..|..|.|..:||.  :.......||::.||..::..
  Rat   382 G-DRITCGGIYIGGCWILTAAHCVRPSRYRNYQVWTSLLDWLKPNSQLAVQGVSRVVVHEKYNGA 445

  Fly   135 LYHNDIALLQLS---SKIE---FNDVTKNITLADIDELEEGDKLTFAGWGSSEAMGTYGRYLQEA 193
            .|.|||||:::.   .|.|   .|.|...:..:.. ..:..|:...:|||
  Rat   446 TYQNDIALVEMKKHPGKKECELINSVPACVPWSPY-LFQPNDRCIISGWG--------------- 494

  Fly   194 SGTYLPVDACREKLQNQ-------DDVDLGHVCVQM----------------DAGQGACHGDTGG 235
                      ||| .||       .:|||...|.:.                |....||.||:||
  Rat   495 ----------REK-DNQKVYSLRWGEVDLIGNCSRFYPGRYYEKEMQCAGTSDGSIDACKGDSGG 548

  Fly   236 PLIDEQQRLV----GIGNWGVPCGR-GYPDVYARTAFYHDWI 272
            ||:.:....|    ||.:||..||: .:|.||.|.|.|.|||
  Rat   549 PLVCKDVNNVTYVWGIVSWGENCGKPEFPGVYTRVASYFDWI 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31266	NP_001138068.1	Tryp_SPc	51..272	CDD:214473	75/256 (29%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	76/257 (30%)
Cfi	NP_077071.1	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555
		SRCR	122..219	CDD:278931
		LDLa	228..258	CDD:197566
		LDLa	264..298	CDD:294076
		Tryp_SPc	361..590	CDD:214473	75/256 (29%)
		Tryp_SPc	362..591	CDD:238113	76/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930